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In sorafenib-resistant hepatocellular carcinoma cells, upregulated peroxisome proliferator-activated receptor delta (PPARδ) enhances glutamine metabolism, characterized by increased production of reducing equivalents — including NADPH and GSH — from glutamine, together with elevated glutamine-derived lipid synthesis
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[DOI] [PubMed] [Google Scholar] 215.Cao S., Wang C., Yan J., Li X., Wen J., Hu C
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