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), that augmented NRF‐1 gene expression in exercised rats, 42 and for the natural precursor of resveratrol, polydatin that enhances SIRT1 expression
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50 , 61 In turn, UA-mediated reduction of inflammatory markers could contribute to blunting their negative regulation of mitochondrial biogenesis effectors, such as PGC1a and SIRT1, thereby allowing the generation of new mitochondria
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