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By contrast, whereas Metro-P2 , resembling the free hydroxy group of Metro , showed a slightly lower MIC of 3.13 µM compared with the parent drug, Metro-P1 and Metro-P3 exhibited an unexpected 30- and 60-fold boost in activity with MIC values of 390 nM and 195 nM, respectively (Fig
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The topical administration of these formulations may serve as a viable therapeutic for the treatment of atopic dermatitis [314]
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