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Combination chemo-antibody therapy with fludarabine (F), cyclophosphamide (C) and rituximab (R) achieves a high CR rate in previously untreated chronic lymphocytic leukemia (CLL)
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They synthesize the thiol-less GSH homologs ophthalmate and norophthalmate as well as the toxic metabolite by-product methylglyoxal (MG) that serve as biomarkers of several diseases in humans
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