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Consistent with our findings in humans that underwent CR, data from multiple lifespan-extending interventions in rodents identified upregulation of CTH as a common signature or potential biomarker of longevity 18
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Moreover, they found a statistically significant increase in the risk of gestational hypertension, the use of antihypertensive drugs, and the premature rupture of membranes (PROM) among women in the intervention group
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