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To examine the combination’s absorption and biodistribution and confirm that it has no harmful effects, the bioavailability of the mixture was first evaluated in a 3D model that mimicked the intestinal barrier
Skin elasticity collagen
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Nintedanib, a multi-target receptor tyrosine kinase inhibitor, targets VEGFR , PDGF , FGFR , FMS-associated tyrosine kinase 3 , and SRC family kinases, thus increasing the efficacy of single-target VEGF drugs 84 ( Table 1 )
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