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○ Eosinophil depletion (PHIL mice) led to increased colitis severity and stronger T helper 17 (Th17) responses, as well as increased production of TNF and IFN γ by CD4 + T cells ( + and CD80 + ) with single-cell transcriptomics, which are induced by cytokines such as IL-33 and IFN γ and exhibit bactericidal and T cell regulatory functions in DSS-colitis
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Metabolism of acetaminophen through the cytochrome P450 pathway results in production of N -acetyl- p -benzoquinone imine (NAPQI), the compound that damages the liver
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