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The decaf group had higher LDL cholesterol and higher apolipoprotein B, a protein that travels with LDL and ties in with heart risk
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These effects depend on integrin α1 and β1 pathway activation, creating functional outcomes of: Enhanced endothelial cell proliferation Increased cell migration to injury sites Improved tubule formation for angiogenesis No cytotoxic effects across wide concentration ranges Hair Follicle Stem Cells Hair follicle stem cells undergo amplification, demonstrated by follicle enlargement in mice
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