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Additionally, flavonoids suppress SREBP-1c-driven lipogenesis and enhance PPAR-α-mediated β-oxidation, thereby alleviating hepatic lipid accumulation ( Quercetin, a flavonol abundant in vegetables and medicinal herbs, activates the Nrf2/HO-1 pathway via MAPK/Nrf2 signaling to restore glutathione levels and reduce serum ALT/AST (Yao et al., 2007
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