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86 demonstrated that Gdf11 expression levels decline in aged hearts and that either targeted myocardial delivery of the Gdf11 gene or recombinant GDF11 protein enhanced cardiac function and effectively reduced infarct size after ischemic injury in aged mice, providing support for the anti-aging function of GDF11
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4.2 Palmitoylation DAT is palmitoylated (16-carbon fatty acid chain) via thioester bonding mainly at Cys580 in the membrane CTD helical region (Rastedt et al., 2017)
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