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D.NicolardiG.CianciulliA.De NuccioF.La PesaV.CarofiglioV.et al (2014)

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Unlike HGPS, Werner syndrome patients develop normally until after puberty, after which many age-related phenotypes manifest, including hair graying, sarcopenia, skin abnormalities, cataracts, atherosclerotic disease, and some cancer, with most patients succumbing to one or more malignancies in their fifth decade of life [167]