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When to seek medical help See a doctor promptly if you have spreading redness or warmth around the site, discharge or a fever, numbness or weakness that does not settle, or any swelling of the face, lips or throat or difficulty breathing, which can signal a rare allergic reaction and is a medical emergency

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6,14 Hepatic encephalopathic changes such as seizures may be seen as a consequence of increased ammonia concentrations in the blood