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This reaction comes up later in the Strecker synthesis of amino acids, which begins with the addition of cyanide ion to an imine, followed by hydrolysis of the nitrile to give the carboxylic acid

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These include action potential production in excitatory tissues used for cell adhesion and interactions, neurotransmitter utilisation in cell signalling such as dopamine, choline and GABA and the calcium uptake and retention regulation by synaptosomes