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Also, in cell and animal models of AD, abnormal neuron excitability has been reported in the cortex and hippocampus, with neurons showing a higher frequency of action potential (AP) firing, as well as a lower recruitment threshold to fire
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In contrast, larvae with ubiquitous suppression of shopper or second-instar larvae homozygous for Df(1)shopper +4 show significantly reduced levels of sulfite oxidase activity (Fig
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