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Therapeutic strategies such as “hit hard and early” and “treat-to-target”, especially with TNF-α inhibitors, can modulate the course of the disease enormously, as they have been shown to lead to drug-free remission, lower disease activity, and higher functional status, which ultimately leads to an improvement in patients’ quality of life [64,65,66]

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Accumulating data reveal that an elevated NLR ratio is a risk factor for NAFLD and NAFLD-related HCC [122, 123]