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Survodutide β GLP-1/Glucagon Dual Agonist for MASH Survodutide (Boehringer Ingelheim/Zealand Pharma) is the GLP-1/glucagon dual receptor agonist with FDA Breakthrough Designation for metabolic dysfunction-associated steatohepatitis (MASH)
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AEs included increased serum creatinine (some cases managed by adjusting dose downward), hypertension (managed with anti-hypertensive meds), alopecia, cutaneous lymphoma, mouth ulcers, and acute gout (managed with allopurinol)
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