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9 Therefore, the advantage of TCM in treating CP and its fibrosis lies in “holistic regulation and multi-target intervention.” It not only focuses on eliminating the cause, such as clearing dampness-heat (exerting anti-inflammatory and antioxidant effects), but also emphasizes restoring the functions of the zang-fu organs (TCM functional organ systems, often corresponding to, but not identical with, anatomical organs), including soothing the liver and regulating qi, strengthening the spleen and harmonizing the stomach (improving metabolic function and nutritional status), and removing pathological products, including activating blood circulation and resolving stasis (ameliorating microcirculation and inhibiting pro-fibrotic pathways), softening hard masses, and dissipating nodules (promoting resolution of fibrotic lesions)