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At week M-92, 42%–49% of participants had achieved endoscopic remission, 65%–75% had achieved HEMI, 66%–74% had achieved histologic remission, and 88%–95% of participants had achieved symptomatic remission

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When present, side effects are typically mild and may include vivid dreams or altered sleep architecture as the brain undergoes increased neuroplastic activity, mild headaches during initial therapy (often resolving within days), temporary changes in appetite, or subtle mood variations during the adaptation period