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Introduction Ammonia, a central element in whole-body nitrogen metabolism Ammonia is an inorganic nitrogen waste product metabolized and produced in all tissues and the principal culprit of hepatic encephalopathy (HE), a spectrum of neuropsychiatric abnormalities derived from liver dysfunction ( Glutamine, a major nontoxic interorgan nitrogen carrier, and hepatic glutamine metabolism Glutamine, the most abundant amino acid in the body, much like ammonia is a major player in whole-body nitrogen metabolism
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