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FDA states that compounded injectable GHK-Cu may pose an immunogenicity risk because of possible aggregation and peptide-related impurities and that human safety data are limited

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The SLC12A family of genes which play a functional role in the pathophysiology of hypertension and cardiovascular disease (43) and VPS16, which encodes a protein involved in vesicle trafficking, are also of particular interest, since changes in these genes have been associated with neurodevelopmental diseases and dementia (44–46)