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Another study found that a 5-HT7 receptor antagonist reduced neural innervation in the mucosal plexus of an IBS-like mouse model by inhibiting the overproduction of neurotrophic factors in the submucosal plexus, highlighting the significant role of 5-HT signaling in the regulation of enteric neuroinflammation [105]

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Size:30ml / 1.01 fl oz

Neutrophils Neutrophils are recruited to necrotic areas by cytokines or DAMPs secreted by KCs, and they then coordinate with liver macrophages to remove necrotic liver cells and tissues (Krenkel et al., 2014)