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Moreover, as the negative effects of DMSO on the cell membrane are well known [1,2,3,15], in parallel to studies involving the direct addition of DMSO to the culture medium, a second method of administration was used—the partial insertion of DMSO into polymerosomes (poly(ethylene glycol) and poly(lactide-co-glycolide) methyl ether block, PEG-PLGA) aimed at eliminating these potentially destructive effects
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